Thoughts about radiocontrast-induced nephropathy from the aspect of cardiology
Moser György1, Légrády Péter2, Ábrahám György2, Herczeg Béla1
1Jász-Nagykun-Szolnok Megyei Hetényi Géza Kórház-Rendelőintézet, Kardiológiai Osztály, Szolnok
2SZTE ÁOK, I. sz. Belgyógyászati Klinika, Nephrologia-Hypertonia Centrum, Szeged
The radiocontrast-induced nephropathy is a complication that puts the function of a vital organ in danger. The risk of this procedure on a scale, compared to the diagnostic (and therapeutic) value of coronarography and coronary interventions, represents similar weight more than ones. In Hungary the number of patients concerned could be a couple of thousand. The authors survey the pathogenesis of this clinical condition as well as the possibilities of its prevention and treatment. The main point to consider is: what effects do agents administered for protection against radiocontrast-induced nephropathy have on systemic hemodynamic, and what is the impact of these effects on renal perfusion and function? A key question is whether cardiac reserves exist to support improvement of systemic and renal hemodynamics status, and if cardiologic and toxicological approaches can augment the prevention and therapy of this primarily nephrologic condition.