Coenzyme-Q10: evidence-based case series in Hungary
█ Review
DOI: 10.26430/CHUNGARICA.2018.48.3.211
Authors:
Nagy Viktor, Borbély Attila1, Kohut László2, Mohay Sándor3, Eke Nándor3, Andrássy Gábor3, Borbola József4, Édes István1
Semmelweis Egyetem, Általános Orvostudományi Kar, II. sz. Belgyógyászati Klinika, Budapest
1Debreceni Egyetem, Általános Orvostudományi Kar, Kardiológiai Tanszék, Debrecen
2Állami Egészségügyi Központ Balatonfüredi Kardiológiai Rehabilitációs Intézet, Kardiológiai Rehabilitációs Osztály, Balatonfüred
3Szt. Ferenc Kórház, Kardiológiai Rehabilitációs Osztály, Budapest
4Gottsegen György Országos Kardiológiai Intézet, Budapest
Summary
The vitamin-like coenzyme Q10 is a compound found naturally in virtually every cell in the human body. It is found in cell membranes and is particularly well known for its role in the electron transport chain in mitochondrial membranes during aerobic cellular respiration. Coenzyme Q10 deficiency has been implicated in several clinical disorders, including heart failure. Primary deficiency has been well described and results from mutations in genes involved in coenzyme Q10 biosynthesis. Based on evidence-based medicine, coenzyme Q10 appears to be a safe supplement for heart failure therapies and also for cardiovascular prevention.
ISSUE: CARDIOLOGIA HUNGARICA | 2018 | VOLUME 48, ISSUE 3
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