Sudden cardiac death risk stratification in arrhythmogenic right ventricular cardiomyopathy
Debreceni Egyetem, Klinikai Központ, Kardiológiai és Szívsebészeti Klinika, Debrecen
Arrhythmogenic right ventricular cardiomyopathy is an inherited disease predominantly with the mutation of desmosomal proteins. Clinically the presence of ventricular arrhythmias and in late stages heart failure is characteristic; however, sudden cardiac death could also be the first manifestation of the disease. Recently several risk factors of sudden cardiac death was identified. Based on the systematic review of these risk factors an international consensus statement (2015) was published also with recommendations on the indication of implantable cardioverter defibrillator (ICD) implantation. According to the document an ICD as a secondary prevention and prophylactically in patients with a severely depressed left and/or right ventricular function (class I.) and also for patients with at least one major risk factor (syncope, non-sustained ventricular tachycardia, moderately depressed left and/or right ventricular function), (class IIa).