Renal denervation: past, today, future?
Szűk Tibor, Leny Andrij, Csanádi Zoltán, Édes István
Debreceni Egyetem, Klinikai Központ, Kardiológiai és Szívsebészeti Klinika, Debrecen
Abstract: The global impact of hypertension cannot be overestimated. The rate of well treated patients, who reach target blood pressure is low, despite of lifestyle changes and drug treatment. Experimental and clinical studies have proven, that the sympathetic nervous system (SNS) plays important role in the triggering and sustaining of hypertension. The blockade of the SNS can be achieved by a device based treatment, renal denervation. However, the efficacy of this invasive method performed with several devices, was brought into doubt by a trial, published in 2014, the Symplicity HTN-3, despite the fact, that safety was obviously proven. The recent Spyral HTN-OFF MED study showed significant positive effect of the Spyral denervation catheter on blood pressure. This summary presents the actualities and its probable future.