SCIENTIFIC JOURNAL of the Hungarian Society of Cardiology

Prediabetes and cardiovascular risk

█ Review

DOI: 10.26430/CHUNGARICA.2018.48.3.221

Járai Zoltán1, 2, Wittmann István3
1Szt. Imre Egyetemi Oktatókórház, Kardiológiai Profil, Budapest
2Semmelweis Egyetem, Általános Orvostudományi Kar, Városmajori Szív- és Érgyógyászati Klinika, Érsebészeti Tanszék, Angiológiai Tanszéki Csoport, Budapest
3Pécsi Tudományegyetem Általános Orvostudományi Kar, Belgyógyászati Klinika és Nephrológiai Centrum, Klinikai Központ, Pécs


Prediabétesz (impaired fasting glucose and/or impaired glucose tolerance) is the preceding state of diabetes mellitus. Prediabetes is a prevalent disease: according to epidemiological studies 25-35% of the adult population is affected, but in elderly (65 years old and above) the prevalence can be even higher (45-50%). The subjects with prediabetes are usually asymptomatic, and this is the reason why this condition rarely diagnosed in spite of clear suggestions of the relevant guidelines for screening of population at high risk. However, the recognition of prediabetes is important, because it causes increased cardiovascular risk. Unequivocal data proves the increased hazard and frequency of subclinical organ damage, and manifest cardiovascular endpoints, like coronary heart disease, stroke and heart failure among patients with prediabetes. More and more data suggests that the treatment of prediabetes with lifestyle measures and pharmacotherapy decreases not only the risk of manifest type 2 diabetes, but also the risk of cardiovascular complications.


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