SCIENTIFIC JOURNAL of the Hungarian Society of Cardiology

Left atrial strain in cardiovascular diseases: an overview of clinical applications

█ Review

DOI: 10.26430/CHUNGARICA.2021.51.1.11

Maria Concetta Pastore1, Giulia Elena Mandoli1, Ciro Santoro2, Luna Cavigli1, Marta Focardi1, Flavio D’Ascenzi1, Matteo Cameli1
1Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Italy
2Department of Advanced Biomedical Science, Federico II University Hospital Naples, Naples, Italy
Corresponding Author:
Matteo Cameli, MD PhD, Department of Medical Biotechnologies, Division of Cardiology University of Siena
Viale Bracci 1, Siena, Italy, e-mail:


Thanks to the increasing evidence on the importance of left atrial (LA) function over LA dimensions to evaluate cardiovascular disease, and to the publication of multicenter data for reference values and to the recent European association of cardiovascular imaging (EACVI)/American society of echocardiography (ASE) consensus document for its standardization (1–3), LA strain by speckle tracking echocardiography (STE) is gaining visibility for the application in daily clinical practice. This parameter allows to analyze LA myocardial deformation and to recognize also concealed myocardial damage (4).

Therefore, being non-invasive, quick and easy to perform, LA strain could offer precious information to basic echocardiography, with high diagnostic and prognostic accuracy, often comparable to other advanced imaging modalities (5). The aim of the present review is to discuss the clinical application of LA strain by STE based on the available evidence.


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