The year in cardiovascular medicine 2020: valvular heart disease
█ Current opinion
Javier Bermejo1, Andrea Postigo1, Helmut Baumgartner2
1Department of Cardiology, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, Facultad de Medicina, Universidad Complutense de Madrid and CIBERCV, Dr Esquerdo 46, Madrid 28007, Spain; 2Department of Cardiology III — Adult Congenital and Valvular Heart Disease, University Hospital Muenster, Albert-Schweitzer-Campus 1, 48149 Münster, Germany
Received 30 September 2020; revised 11 November 2020; editorial decision 10 December 2020; accepted
16 December 2020; online publish-ahead-of-print 3 January 2021
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The Author(s) 2021. Published by Oxford University Press on behalf of the European Society of Cardiology.
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Valvular heart disease (VHD) is one of the most rapidly changing disciplines in cardiovascular medicine. During the past year, important basic research has provided new insight into disease mechanisms and identified new potential targets for pharmacological treatment. Despite the unequivocal impact of COVID-19 on global research and management of VHD (1), the results of landmark clinical trials with percutaneous devices have become available. Aspects of adjuvant medical therapies after device implantation have also been clarified. Technical improvements in next-generation valvular medical devices are taking place in parallel, showing promising preliminary clinical results. As the risk related to interventional procedures and their consequences is becoming lower, new opportunities for an earlier treatment arise. The most important achievements during 2020 are summarized herein.