SCIENTIFIC JOURNAL of the Hungarian Society of Cardiology

The year in cardiovascular medicine 2021: acute cardiovascular care and ischaemic heart disease

█ Current opinion

Susanna Price1, 2*, Jason Katz3,
Christoph C. Kaufmann4, Kurt Huber4, 5, 6
1Consultant Cardiologist & Intensivist, Royal Brompton Hospital, London, UK;
2National Heart & Lung Institute, Imperial College, London, UK;
3Duke University, Durham, NC, USA;
43rd Medical Department, Cardiology and Intensive Care Medicine, Klinik Ottakring (Wilhelminenhospital), Montleartstrasse 37, 1160, Vienna, Austria;
5Medical School, Sigmund Freud University, Vienna, Austria; and
6Ludwig Boltzmann Institute for Cardiovascular Research, Vienna, Austria


In a year when COVID-19 continued to dominate health­care, its impact on cardiovascular disease in the acute and emergency settings remained evident. The cardiovascular literature documented persistent disruption in healthcare delivery, with continued reduction in patients presenting with ST-segment elevation myocardial infarction (STEMI) and increased late presentations of STEMI, infarct size, and complications (1, 2), delay in revascularization (3), reduction in admissions for acute heart failure (AHF), and an associated increased in-hospital AHF mortality (4). The extent, nature, and aetiology of COVID-19-related cardiac injury were the focus of numerous studies (5, 6), PIMS-TS (paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2) became well recognized as a disease entity with potential significant cardiac involvement, and defined diagnostic criteria and treatment strategies (7, 8). The important but rare side effect of mRNA vaccine-related myocarditis emerged (9), and the syndrome of thrombosis with thrombocytopaenia after ChAdOx1 NcoV-19 vaccination (10) prompted development of a novel score (FAPIC) to predict mortality (11). Despite this immense disruption to healthcare, significant advances were nonetheless made in the fields of acute coronary syndromes (ACS), ischaemic heart disease, and acute cardiovascular care, with a number of important papers published in the European Heart Journal and elsewhere that significantly furthered our knowledge in these fields.


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